Slow but Steady or Bureaucratic Quagmire?

Slow but steady wins the drug race

Without the SNF-6 acetylcholine transporter (bottom) mutant muscles fall apart. K im /M ac m ill an they are mutant for various members of the dystrophinglycoprotein complex (DGC), which links intracellular actin to extracellular laminin. But now, Hongkyun Kim, Steven McIntire (University of California, San Francisco, CA), and colleagues suggest that loss of the DGC results in loss of an associ...

Travellers' diarrhoea: slow but steady progress.

Pediatric vesicoureteral reflux: Slow but steady steps

Vesicoureteral reflux (VUR) is a common urological anomaly that is found in 1% of children. VUR can cause recurrent febrile urinary tract infection (UTI). The recurrent infections can result in renal scarring, which can lead to renal hypertension and end-stage renal disease. Thus, our therapeutic goal is to prevent febrile UTI in the short term and, in the long term, to preserve renal function ...

Quality guidelines for systemic lupus erythematosus: slow but steady progress.

3. Information on permissions/orders of reprints in rheumatology and related fields. Silverman featuring research articles on clinical subjects from scientists working is a monthly international serial edited by Earl D.

Clinical trials of transplant tolerance: slow but steady progress.

The search for tolerance therapies that would thwart the alloimmune response following organ transplantation while preserving a patient's protective immune response has been a formidable goal for clinical immunologists. Over the past few decades, a more detailed understanding of the molecular events associated with T-cell recognition and activation has demonstrated the feasibility of various to...